Kuo T (corresponding author), Du W, Miyachi Y, Dadi PK, Jacobson DA, Segrè D, Accili D. Antagonistic epistasis of Hnf4a and Foxo1 metabolic networks through enhancer interactions in beta-cell function. Mol Metab. 2021 Nov;53:101256.
Kitamoto T, Kuo T, Okabe A, Kaneda A, Accili D. An integrative transcriptional logic model of hepatic insulin resistance. Proc Natl Acad Sci U S A. 2021 Nov 9;118(45):e2102222118.
Miyachi Y, Kuo T, Son J, Accili D. Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets. PLoS One. 2021 Nov 29;16(11):e0260526.
Chen TC, Kuo T, Dandan M, Lee RA, Chang M, Villivalam SD, Liao SC, Costello D, Shankaran M, Mohammed H, Kang S, Hellerstein MK, Wang JC. The role of striated muscle Pik3r1 in glucose and protein metabolism following chronic glucocorticoid exposure. J Biol Chem. 2021 Feb 7; 100395.
Kuo T, Kraakman MJ, Damle M, Gill R, Lazar MA, Accili D. Identification of C2CD4A as a human diabetes susceptibility gene with a role in β-cell insulin secretion. Proc Natl Acad Sci U S A. 2019 Oct 1;116(40):20033-20042. *Covered by Columbia University Medical Center News: https://www.cuimc.columbia.edu/news/new-diabetesgene-found
Kuo T (corresponding author), Damle M, Gonzales BJ, Egli D, Lazar MA, Accili D. Induction of α cell-restricted Gc in dedifferentiating β cells contributes to stress-induced β-cell dysfunction. JCI Insight. 2019 May 23;5. pii: 128351.
Fan J, Kim-Muller JY, Son J, Kuo T, Larrea D, Garcia C, Kitamoto T, Kraakman MJ, Du W, Owusu-Ansah E, Cirulli V, Accili D. Cyb5r3 Links FoxO1-dependent Mitochondrial Dysfunction With β-cell Failure. Mol Metab. 2020 April;34:97-111.
Chen TC, Benjamin DI, Kuo T, Lee RA, Li ML, Mar DJ, Costello DE, Nomura DK, Wang JC. The glucocorticoid-angptl4-ceramide axis induces insulin resistance through PP2A and PKCζ. Science Signaling. 2017;10(489).
Kuo T, Chen TC, Lee RA, Nguyen NHT, Broughton AE, Zhang D, Wang JC. Pik3r1 is required for glucocorticoid-induced perilipin 1 phosphorylation in lipid droplet for adipocyte lipolysis. Diabetes. 2017; 66(6):1601-1610.
Reischauer S, Stone OA, Villasenor A, Chi N, Jin SW, Martin M, Lee MT, Fukuda N, Marass M, Witty A, Fiddes I, Kuo T, Chung WS, Salek S, Lerrigo R, Alsiö J, Luo S, Tworus D, Augustine SM, Mucenieks S, Nystedt B, Giraldez AJ, Schroth GP, Andersson O, Stainier DY. Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification. Nature. 2016; 535(7611):294-8.
Accili D, Talchai SC, Kim-Muller JY, Cinti F, Ishida E, Ordelheide AM, Kuo T, Fan J, Son J. When β-cells fail: lessons from dedifferentiation. Diabetes, Obesity & Metabolism. 2016; 18 suppl 1:117-22. Review.
Kuo T, Kim-Muller JY, McGraw TE, Accili D. Altered plasma profile of antioxidant proteins as an early correlate of pancreatic β-cell dysfunction. J Biol Chem. 2016; 291(18):9648-56.
Kuo T, Liu PH, Chen TC, Lee RA, New J, Zhang D, Lei C, Chau A, Tang Y, Cheung E, Wang JC. Transcriptional regulation of FoxO3 gene by glucocorticoids in murine myotubes. American Journal of Physiology, Endocrinology and Metabolism. 2016; 310(7):E572-85.
Kuo T, McQueen A, Chen TC, Wang JC. Regulation of glucose homeostasis by glucocorticoids. Adv Exp Med Biol. 2015;872:99-126. Book Chapter.
Kuo T, Chen TC, Yan S, Foo F, Ching C, McQueen A, Wang JC. Repression of glucocorticoid-stimulated angiopoietin-like 4 gene transcription by insulin. J Lipid Res. 2014 May;55(5):919-28.
Kuo T, Harris A, Wang JC. Metabolic functions of glucocorticoid receptor in skeletal muscle. Mol Cell Endocrinol. 2013 Mar 21. Review.
Kuo T, Lew MJ, Mayba O, Harris CA, Speed TP, Wang JC. Genome-wide analysis of glucocorticoid-receptor-binding sites in myotubes identifies gene networks modulating insulin signaling. Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28):11160-5. *Recommended by F1000
Wang JC, Gray NE, Kuo T, Harris CA. Regulation of triglyceride metabolism by glucocorticoids. Cell Biosci. 2012 May 28;2(1):19. Review.
Lancman JJ, Zvenigorodsky N, Gates KP, Zhang D, Solomon K, Humphrey RK, Kuo T, Setiawan L, Verkade H, Chi YI, Jhala US, Wright CV, Stainier DY, Dong PD. Specification of hepatopancreas progenitors in zebrafish by hnf1ba and wnt2bb. Development. 2013 Jul;140(13):2669-79.
Koliwad SK, Kuo T, Shipp LE, Gray NE, Backhed F, So AY, Farese RV Jr, Wang JC. Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoid-regulated triglyceride metabolism. J Biol Chem. 2009 Sep 18;284(38):25593-601.
Munson C, Huisken J, Bit-Avragim N, Kuo T, Dong PD, Ober EA, Verkade H, Abdelilah-Seyfried S, and Stainier DY. Regulation of Neurocoel Morphogenesis by Pard6gammab. Dev. Bio. 2008 Dec 1;324(1):41-54.